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KMID : 0360220200610080868
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Journal of the Korean Ophthalmological Society
2020 Volume.61 No. 8 p.868 ~ p.875
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Anti-staphylococcal Effect of a Nephrite-containing Contact Lens Storage Case
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Park Su-Hwan
Lee Seung-Uk
Kim Yoon-Kyung
Yu Hak-Sun
Park Sung-Hee
Ahn Jung-Hyo
Kim Su-Jin
Shin Jong-Hoon
Lee Ji-Eun
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Abstract
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Purpose: To compare the anti-staphylococcal effect of nephrite-containing contact lens (CL) storage cases and conventional CL storage cases.
Method: The degree of proliferation and adhesion of Staphylococcus aureus (S. aureus) on first- to third-generation silicone hydrogel contact lenses (SHCLs) was analyzed through comparison of 5% nephrite-containing CL storage cases and conventional CL storage cases. The degree of adhesion of S. aureus to the CL was also compared between 1% or 5% nephrite solution and multipurpose solution (MPS).
Result: Nephrite-containing CL storage cases showed a significant inhibitory effect on S. aureus proliferation (p = 0.004) and significantly reduced the number of adherent S. aureus on all first- to third generation SHCLs compared with conventional CL storage cases (p = 0.026, p = 0.043, and p = 0.001, respectively). The anti-staphylococcal effect of 1% and 5% nephrite solutions was not significantly better than that of MPS.
Conclusions: Nephrite shows potential as a next-generation substance for reducing infectious keratitis caused by S. aureus when added to CL storage cases.
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KEYWORD
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Contact lens storage case, Infectious keratitis, Multipurpose solution, Nephrite, Staphylococcus aureus
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